The world's #1 cause of irreversible blindness

Glaucoma, a group of eye diseases that can result in optic nerve damage and irreversible blindness, is one of the most vexing issues in healthcare, affecting 60–80 million people globally.

What Causes Glaucoma?

The exact cause of optic nerve damage from glaucoma is not fully understood, but high eye pressure is most often associated with the disease. High intraocular pressure (IOP) left untreated may result in irreversible optic nerve damage that can ultimately lead to blindness.

A healthy eye drains continuously
and without obstruction

Blockages in the natural drainage system can
develop, increasing intraocular pressure

A life-long eye disease called Glaucoma
develops, which can cause
irreversible vision loss

The Varying Types of Glaucoma

The two main types of glaucoma are open-angle glaucoma and angle-closure glaucoma. Each is most commonly marked by an increase of IOP inside the eye.

Sight Sciences surgical systems are intended to lower pressure in patients suffering from open-angle glaucoma, the most common form of glaucoma that accounts for 90% of all cases*.


In open-angle glaucoma, the drainage angle formed by the cornea and the iris remains open, but the eye’s drainage canal remains blocked, resulting in a slow increase in eye pressure.

Patients may not notice they have lost vision until the disease has progressed significantly.

*Source: Glaucoma Research Foundation

Current Treatment Options

There is no cure for glaucoma, but there are several treatments intended to reduce the intraocular pressure associated with the disease. The cost and burden of such treatment methods, which involve daily, costly, and sometimes painful eye drops or highly invasive surgery, have driven the development of novel, less invasive surgical approaches.

Glaucoma treatment can vary as the disease progresses. More recently, less invasive glaucoma devices have been approved that can be delivered through only a single, sutureless corneal incision and can slow the progression of disease, delay the need for a more invasive surgery, and often reduce the medication burden for patients.

Eye Drops
The most common treatment for mild glaucoma is prescription eye drops. However, studies show that at least 50% of patients are not compliant with their medications within 6 months of diagnosis. 1
SLT Laser
As the disease progresses and medication is unable to control eye pressure, laser surgery is employed to reduce IOP.
Microinvasive Stents and Shunts
In contrast to the current options of daily eye drops or highly invasive surgery, Sight Sciences has developed innovative and minimally invasive glaucoma surgical systems designed to restore natural aqueous outflow and reduce IOP.
Learn More about VISCO™360
In contrast to the current options of daily eyer drops or highly invasive surgery, Sight Sciences has developed innovative and minimally invasive glaucoma surgical systems designed to improve natural arqueous outflow and reduce IOP.
Learn More about TRAB™360
Filtering Surgery
+ Tube Shunt
To mitigate the progression of the disease and subsequent loss of vision, end-stage glaucoma patients undergo highly invasive filtering surgery that includes implantation of tube shunts.

The information listed in the diagram above is the expressed view of Sight Sciences and is not to be used for treatment purposes.

1. Mansberger S., Am J Ophthalmol. 2010; 149(1):1.

Learn more about Sight Sciences novel, minimally invasive glaucoma surgery systems.