The world's #1 cause of irreversible blindness

Glaucoma, a group of eye diseases that can result in optic nerve damage and irreversible blindness, is one of the most vexing issues in healthcare, affecting 60–80 million people globally.

What Causes Glaucoma?

The exact cause of optic nerve damage from glaucoma is not fully understood, but high eye pressure is most often associated with the disease. High intraocular pressure (IOP) left untreated may result in irreversible optic nerve damage that can ultimately lead to blindness.

A healthy eye drains continuously
and without obstruction

Blockages in the natural drainage system can
develop, increasing intraocular pressure

A life-long eye disease called Glaucoma
develops, which can cause
irreversible vision loss

The Varying Types of Glaucoma

The two main types of glaucoma are open-angle glaucoma and angle-closure glaucoma. Each is most commonly marked by an increase of IOP inside the eye.

Sight Sciences surgical systems are intended to lower pressure in patients suffering from open-angle glaucoma, the most common form of glaucoma that accounts for 90% of all cases*.


In open-angle glaucoma, the drainage angle formed by the cornea and the iris remains open, but the eye’s drainage canal remains blocked, resulting in a slow increase in eye pressure.

Patients may not notice they have lost vision until the disease has progressed significantly.

*Source: Glaucoma Research Foundation

1. Mansberger S., Am J Ophthalmol. 2010; 149(1):1.

Learn more about Sight Sciences' novel, minimally invasive glaucoma surgery systems.